Optimising personalised cancer diagnosis and treatment

Summer school : 20 June – 1st July 2022

Edition 2022

Welcome from the Director

Advances in precision medicine increasingly allow healthcare providers to provide and plan individualized care for cancer patients. Precision Oncology invites participants to rethink current approaches, methods and models from a global perspective, integrating artificial intelligence and big data derived from medical imaging, genetic testing and measurement of clinical outcomes.

The program comprises four scientific pillars: clinical research; medical physics; biology and gene expression; environment, prediction, prevention. In addition, participants work in groups on cross-cutting innovation projects addressing unmet needs in the areas of prevention, detection and diagnosis, treatment & follow-up.

Precision Oncology gives participants the opportunity to step out of their comfort zone to acquire or strengthen transversal skills and thus be better prepared to interact and collaborate with key players in cancer research and treatment.

As a certified medical physicist and tenured professor of medical physics at Grenoble-Alpes University, my teaching and research projects are devoted to the application of physics and computing to health care and delivery.

 

Prof. Jean-François ADAM
Associate professor, medical physicist at Université Grenoble-Alpes

About the school

Advances in precision medicine are enabling health-care providers to go beyond the “one-size-fits all” approach and instead to offer and plan individualised care to cancer patients.

The molecular characterization of tumours and their micro-environment, together with the appreciation of their spatial and temporal heterogeneity, are at the forefront of precision oncology.

Increased understanding of the molecular pathways and complex gene-environment interactions which underlie cancer development, is opening the path to more effective prevention, optimised treatment selection and delivery, and enhanced clinical outcomes, including quality of life.

Many challenges persist, however

  • Only a fraction of patients currently benefits from personalised treatment plans,
  • Treatment resistance continues to be a major constraint limiting their efficacy,
  • The evolving nature of tumours requiring treatment adaption is not sufficiently taken into account,
  • The implementation of precision medicine is a lengthy and costly process requiring a rethinking of the current methodology for new treatment validation and a possible re-organisation of the current health care systems.

The Precision Oncology school prompts participants to rethink current approaches, methods and models from a global perspective, notably patient-centred design and innovation integrating Artificial Intelligence and Big Data derived from medical imaging, genetic testing and clinical outcome measures.

Delivered by a faculty of more than 30 international experts, Precision Oncology offers an intensive and challenging programme blending a range of advanced courses, interactive talks with experts from outside the field and structured project work on a patient-centred innovation project.

Programme

Advanced courses on :

  • Clinical Research
  • Medical Physics
  • Biology & Gene Expression
  • Environment, Prediction, Prevention

 

Interactive talks on :

  • Data Privacy – the regulatory framework
  • Ethical issues
  • Patient involvement

Interactive group work and coaching on innovation projects addressing :

  • Prevention
  • Early detection & extended diagnosis
  • Personalised treatment
  • Follow-up / Quality of life / Survivorship

Having gained a deeper understanding of how personalized medicine works in practice, participants will be better prepared to interact and collaborate with leading players in cancer research and treatment.

Innovation Projects

When registering for the school, participants are asked to submit an idea / project proposal for taking precision oncology to a new level in one of four areas :

  • Prevention
  • Early detection & extended diagnosis
  • Personalised treatment
  • Follow-up / Quality of life / Survivorship

Ideas should be innovative but realistic and as far as possible address unmet needs in cancer care.

The Steering Committee will select up to six of these ideas to be used in the group work innovation and entrepreneurship sessions.

Project initiators will not necessarily be the group leaders. Each group is free to organise its innovation team.

Precision Oncology will likely take participants out of their comfort zone, giving them the opportunity to acquire or strengthen transversal skills such as:

  • Capacity for Calculated Risk
    à Success happens when preparation meets opportunity
  • Open and Critical Thinking
    à Ability to combine critical thinking with an open mind
  • Initiative with Follow-Through
    à Embarking upon new ventures even when the going gets tough

Student testimonies

Steering Committee

Prof. Jean-François ADAM
Université Grenoble Alpes (UGA)

Prof. Vincent GREGOIRE
Centre Léon Bérard (CLB)

Mylène HONORAT
CLARA

Florence LE CALVEZ-KELM
International Agency for Research on Cancer (IARC)

Caroline MOYRET-LALLE
University Claude Bernard Lyon 1 (UCBL1)

Alessandro RAIMONDO
CERN

A collaborative partnership involving

With the support of