Optimising personalised cancer diagnosis and treatment

Phase 1: 2 May – 18 June 2023
PREPARATION 1 (on-line / Individual work)

Phase 2: 19 June – 2 July 2023
PREPARATION 2 (on-line / Live sessions)

Phase 3: 3 – 10 July 2023
APPLICATION (face-to-face summer school)

Programme of the school in 2022

Welcome from the Director

Advances in precision medicine increasingly allow healthcare providers to provide and plan individualized care for cancer patients. Precision Oncology invites participants to rethink current approaches, methods and models from a global perspective, integrating artificial intelligence and big data derived from medical imaging, genetic testing and measurement of clinical outcomes.

The program comprises four scientific pillars: clinical research; medical physics; biology and gene expression; environment, prediction, prevention. In addition, participants work in groups on cross-cutting innovation projects addressing unmet needs in the areas of prevention, detection and diagnosis, treatment & follow-up.

Precision Oncology gives participants the opportunity to step out of their comfort zone to acquire or strengthen transversal skills and thus be better prepared to interact and collaborate with key players in cancer research and treatment.

As a certified medical physicist and tenured professor of medical physics at Grenoble-Alpes University, my teaching and research projects are devoted to the application of physics and computing to health care and delivery.

 

Prof. Jean-François ADAM
Associate professor, medical physicist at Université Grenoble-Alpes

Context

Advances in precision medicine are enabling health-care providers to go beyond the “one-size-fits all” approach and instead to offer and plan individualised care to cancer patients.

The molecular characterization of tumours and their micro-environment, together with the appreciation of their spatial and temporal heterogeneity, are at the forefront of precision oncology.

Increased understanding of the molecular pathways and complex gene-environment interactions which underlie cancer development, is opening the path to more effective prevention, optimised treatment selection and delivery, and enhanced clinical outcomes, including quality of life.

Goal of the school

Develop innovation projects in oncology through a transversal and transdisciplinary programme focusing on:

  1. Management (teamwork, project management, motivation within the group, scientific communication): Acquisition of “soft skills” that go beyond traditional university courses
  2. Technological advances (gene expression, image processing, …): Opening up to other scientific and technological fields (multidisciplinary)
  3. Entrepreneurship (innovation, business model, marketing, communication, intellectual property, ethics): Raising awareness of entrepreneurship as a potential career pathway

The challenge

  • Only a fraction of patients currently benefits from personalised treatment plans,
  • Treatment resistance continues to be a major constraint limiting their efficacy,
  • The evolving nature of tumours requiring treatment adaption is not sufficiently taken into account,
  • The implementation of precision medicine is a lengthy and costly process requiring a rethinking of the current methodology for new treatment validation and a possible re-organisation of the current health care systems.

Programme

Precision Oncology offers an INTENSIVE and challenging programme over three phases:

Phase 1 : Fundamentals (individual work):

A series of pre-recorded talks on the four scientific pillars

 

Phase 2: Fundamentals (knowledge assessment)

A series of live interactive sessions by video conference

Phase 3 : Application (face-to-face summer school)

  • Practical applications on the four scientific pillars
  • A day with the Medical Applications group at CERN
  • Interactive sessions on innovation, entrepreneurship and scientific communication
  • Mentored team-work on a patient-centred innovation project
  • Project presentations in front of a panel of experts

Innovation Projects

When registering for the school, participants are asked to submit an idea / project proposal for taking precision oncology to a new level in one of four areas :

  • Prevention
  • Early detection & extended diagnosis
  • Personalised treatment
  • Follow-up / Quality of life / Survivorship

Ideas should be innovative but realistic and as far as possible address unmet needs in cancer care.

The Steering Committee will select up to six of these ideas to be used in the group work innovation and entrepreneurship sessions.

Student testimonies

Steering Committee

Prof. Jean-François ADAM
Université Grenoble Alpes (UGA)

Prof. Vincent GREGOIRE
Centre Léon Bérard (CLB)

Mylène HONORAT
CLARA

Florence LE CALVEZ-KELM
International Agency for Research on Cancer (IARC)

Caroline MOYRET-LALLE
University Claude Bernard Lyon 1 (UCBL1)

Alessandro RAIMONDO
CERN

A collaborative partnership involving

With the support of